Police have charged a 47-year-old woman from New Norfolk with Attempted Murder in relation to an isolated incident at a New Norfolk residence on Humphrey Street last night.

She has been detained in custody and will appear before the Hobart Magistrates Court today.

A 74-year-old man from New Norfolk remains in the Royal Hobart Hospital in a critical condition after sustaining gunshot and stab wounds.

Police reassure the community this was an isolated incident, between people known to each other, and there is no threat to the wider community.