Police are investigating a two-car crash on the Tasman Highway west of the Midway Point roundabout around 10.30am today.

A red Mitsubishi SUV travelling in an easterly direction crossed to the incorrect side of the roadway and collided with a red Mazda sedan travelling in a westerly direction.

The driver of the Mitsubishi was transported to the Royal Hobart Hospital for observation whilst the driver of the Mazda was uninjured.

The crash caused moderate damage to both vehicles.

Tasmania Police would like to thank the public for their patience during traffic disruptions, which supported the safe management of the crash scene.

Police are continuing to investigate and would like to speak to anyone who witnessed the crash. Information can be provided to Tasmania Police on 131444 or to Crime Stoppers anonymously on 1800 333 000.