Burnie police are calling for information over significant damage to a Burnie business overnight.

Police were called to Wilson Street about 11.20pm Tuesday after reports two people were breaking office windows at a commercial property.

About 40 to 45 windows had been broken causing an estimated $45,000 worth of damage.

Forensic officers attended the scene, and the matter is now being investigated by Western CIB.

Anyone with information should contact Burnie Police on 131 444 or Crime Stoppers anonymously via crimestopperstas.com.au