Police are investigating a suspicious structure fire at Clarendon Vale last night.

Tasmania Fire Service and Tasmania Police attended a report of a house fire in Mockridge Road, Clarendon Vale about 10.15pm last night.

Upon arrival, the residence was well alight.  The fire was extinguished by fire crews a short time later.

The occupants of the residence were not home at the time of the fire and there were no injuries as a result of the incident.

The residence is owned by Mission Australia and the estimated value of the damage is approximately $50,000.

Forensic Services and CIB officers also attended the scene.

At this stage, police are treating the fire as suspicious and investigations are continuing as to the cause of the fire.

Anyone with information may anonymously contact Crime Stoppers on 1800 333 000 or Bellerive CIB on 131444.